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You are here: McMaster Institute for Music and the Mind > Publications > Demonstration and validation of kernel density estimation (KDE) for spatial meta-analyses of neuroimaging data

Michel Belyk, Steven Brown, and Sonja A Kotz (2017)

Demonstration and validation of kernel density estimation (KDE) for spatial meta-analyses of neuroimaging data

Data in Brief, 13:346-352.

The data presented in this article are related to the research article entitled “Convergence of semantics and emotional expression within the IFG pars orbitalis” (Belyk et al., 2017). The research article reports a spatial meta-analysis of brain imaging experiments on the perception of semantic compared to emotional communicative signals in humans. This Data in Brief article demonstrates and validates the use of Kernel Density Estimation (KDE) as a novel statistical approach to neuroimaging data. First, we performed a side-by-side comparison of KDE with a previously published meta-analysis that applied activation likelihood estimation, which is the predominant approach to meta-analyses in cognitive neuroscience. Second, we analyzed data simulated with known spatial properties to test the sensitivity of KDE to varying degrees of spatial separation. KDE successfully detected true spatial differences in simulated data and displayed few false positives when no true differences were present. R code to simulate and analyze these data is made publicly available to facilitate the further evaluation of KDE for neuroimaging data and its dissemination to cognitive neuroscientists.

meta-analysis